Clinical research on effect of TCM treatment beginning with Fei in treating systemic lupus erythematosus for reducing incidence of complicated infection.
- Author:
Xiao-juan TAO
1
;
Hong-xia ZHENG
;
Jian-ning YU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Anti-Bacterial Agents; therapeutic use; Cyclophosphamide; therapeutic use; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Lupus Erythematosus, Systemic; complications; drug therapy; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy; Prednisone; therapeutic use; Respiratory Tract Infections; etiology; prevention & control; Treatment Outcome
- From: Chinese Journal of Integrated Traditional and Western Medicine 2007;27(1):33-36
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of TCM treatment beginning with Fei in reducing the incidence of complicated infection and the antibiotic utilization rate in patients with systemic lupus erythematosus (SLE).
METHODSOne hundred and ten SLE patients were randomly assigned to 2 groups equally, the control group treated with the conventional Western medicinal treatment and the treated group treated with the same conventional treatment and SLE I formula (in active stage) or SLE II formula (in silent period) additionally.
RESULTSAfter 3-month and 6-month treatment, the total effective rate was 83.64% , 87.27% in the treated group, and 78.18%, 81.82% in the control group respectively, showing insignificant difference between the two groups. It lowered in both groups after 1-year treatment, however, which in the treated group (78.18%) was higher than that in the control group (60.00%, P < 0.05). But the difference became insignificant again after 2-year treatment, it being 87.27% in the treated group and 72.73% in the control group. The incidence of complicated infection and antibiotic utilization rate in the 2-year treatment was 23.6%, 55.0% respectively in the treated group, markedly lower than those (50.9% and 100%) in the control group respectively (P < 0.01).
CONCLUSIONTCM treatment beginning with Fei could decrease the incidence of complicated infection and the antibiotic utilization rate in SLE patients.
