Clinical observation on effect of jieguxujin granule in promoting union of fracture.
- Author:
Teng ZHOU
1
;
Xiang-dong CHU
;
Xiao-yan ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; blood; Child; Drugs, Chinese Herbal; therapeutic use; Female; Femoral Fractures; drug therapy; Fracture Healing; drug effects; Fractures, Bone; drug therapy; Humans; Humeral Fractures; drug therapy; Male; Middle Aged; Phytotherapy; Tibial Fractures; drug therapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2006;26(2):123-127
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the clinical effect of Jieguxujin granule (JGXJG) on fracture and its effect on serum content of calcitonin gene related peptide (CGRP).
METHODSFour hundred patients with fracture were randomly divided into 2 groups, the JGXJG treated group and the control group treated with Sanqi tablet (SQT). Serum CGRP was tested with radioimmunoassay once every 3 days for 5 times, and X-ray examination was taken once each week for 10 weeks.
RESULTSThe healing time of fracture and osteotylus forming time in the JGXJG group was shorter than those in the SQT group significantly (P < 0.005). Serum CGRP content in JGXJG group was higher remarkably (P < 0.05, P < 0.01).
CONCLUSIONJGXJG showed evident effect in promoting union of fracture healing, it could also increase the CGRP content in serum.
