Research progress of relationship between exosomes and breast cancer.
- Author:
Tao-Ling BI
1
;
Jin-Jian SUN
1
;
Yu-Zi TIAN
1
;
Ye-Fang ZHOU
2
Author Information
1. Department of Cellular Biology, School of Life Sciences, Central South University and State Key Laboratory of Medical Genetics, Changsha 410108, China.
2. Department of Cellular Biology, School of Life Sciences, Central South University and State Key Laboratory of Medical Genetics, Changsha 410108, China. zhouyefang191@126.com.
- Publication Type:Journal Article
- MeSH:
Breast Neoplasms;
Cell Movement;
Exosomes;
Humans;
RNA
- From:
Acta Physiologica Sinica
2016;68(3):352-358
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are nanosized small membrane microvesicles of endocytic origin secreted by most cell types. Exosomes, through its carrying protein or RNA from derived cells, affect gene regulation networks or epigenetic reorganization of receptor cell, and then modulate the physiological processes of cells. Studies have shown that external exosomes secreted by breast cancer cells or other cells play an important role in the development of tumor, including cell migration, cell differentiation and the immune response, etc. In this article, the latest studies were summarized to provide an overview of current understanding of exosomes in breast cancer.
