The mechanisms of medial vascular calcification.
- Author:
Yi-Han LIU
1
;
Wei KONG
2
Author Information
1. Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China.
2. Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China. kongw@bjmu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Calcinosis;
Humans;
Tunica Intima;
Vascular Calcification
- From:
Acta Physiologica Sinica
2016;68(5):592-610
- CountryChina
- Language:Chinese
-
Abstract:
Vascular calcification is an active, invertible and highly regulated pathophysiological process, characterized by the deposition of hydroxyapatite crystal in vascular wall. Vascular calcification is classified into two types based on the sites of calcification: intimal atherosclerotic calcification and Mönckeberg's medial calcification. Medial vascular calcification is a pathological phenomenon commonly existed in diabetes, chronic kidney failure and aging. The current review summarizes the mechanisms of medial vascular calcification.
