Review of Anemone raddeana Rhizome and its pharmacological effects.
10.1007/s11655-017-2901-2
- Author:
Shu-Ling WANG
1
;
Zhen-Kun ZHAO
2
;
Jian-Feng SUN
1
;
Yun-Ting SUN
3
;
Xiao-Qing PANG
1
;
Zhao-Wu ZENG
1
;
Tian XIE
4
Author Information
1. Medical College, Hangzhou Normal University, Hangzhou, 311121, China.
2. Suzhou Dongrui Pharmaceutical Co., Ltd., Suzhou, 215000, Jiangsu Province, China.
3. Department of Acupucture, Hangzhou Traditional Chinese Medicine Hospital, Hangzhou, 311121, China.
4. Medical College, Hangzhou Normal University, Hangzhou, 311121, China. xbs@dljg.sina.net.
- Publication Type:Journal Article
- Keywords:
Anemone raddeana Rhizome;
Chinese medicine;
analgesic;
anti-inflammatory;
anticancerous;
antimicrobial;
pharmacological effect;
phytochemical constituent
- From:
Chinese journal of integrative medicine
2018;24(1):72-79
- CountryChina
- Language:English
-
Abstract:
The chemical compositions of Anemone raddeana Rhizome, a kind of traditional Chinese medicine, were reviewed, along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins. A. raddeana Rhizome is used to treat neuralgia and rheumatism, and is rich in triterpenoid saponins, most of which are pentacyclic, with oleanane as the nucleus. So far, 37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous, antimicrobial, anti-inflammatory, analgesic, antipyretic, anticonvulsive, antihistaminic, and sedative. It has also been used for the induction of the humoral immune response and treatment of liver fibrosis in chronic hepatitis. However, the herb also has hemolytic effects and can be toxic, which limits its clinical application. Further studies are needed on the pharmaceutical functions, mechanisms, and immunological responses to contribute to the herb's clinical applications.
