Effect of overload environment on IGF-1 expression of osteoblasts.
- Author:
Juanfang SHANG
1
;
Liling TANG
;
Xufeng NIU
;
Yuanliang WANG
Author Information
1. Key Lab. of Biomechanics & Tissue Engineering under the State Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Insulin-Like Growth Factor I;
biosynthesis;
genetics;
Osteoblasts;
cytology;
metabolism;
Osteogenesis;
RNA, Messenger;
biosynthesis;
genetics;
Stress, Mechanical;
Weight-Bearing;
physiology
- From:
Journal of Biomedical Engineering
2006;23(6):1363-1366
- CountryChina
- Language:Chinese
-
Abstract:
In the study of the relationship between cells overloading and the formation, regeneration and growth of bone, the text discussed osteoblasts express IGF-1 variation under overloading environment. The research of overloading on cellular level may elucidate the mechanical effect on the formation, regeneration and growth of bone and the mechanism of cell response in bone.
