Theoretical evaluation of the use of KT/Vurea and Ccr as indexes of peritoneal dialysis adequacy.
- Author:
Yisheng SHAN
1
;
Xinkui TIAN
;
Tao WANG
Author Information
1. Institute of Nephrology, First Hospital, Peking University, Beijing 100034, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers;
metabolism;
Blood Urea Nitrogen;
Creatinine;
metabolism;
Humans;
Peritoneal Dialysis, Continuous Ambulatory;
Urea;
metabolism
- From:
Journal of Biomedical Engineering
2007;24(1):140-144
- CountryChina
- Language:Chinese
-
Abstract:
Urea clearance index (KT/Vurea) and creatinine clearance weekly (Ccr) are main indexes to evaluate dialysis adequacy. In order to discuss whether they are suitable to evaluate peritoneal dialysis adequacy, we applied trans-peritoneum transport kinetic model and explored the transport characteristics of fluid and various solutes. We found that: (1) There was no specific relationship among the removal of solutes with different molecular weights; (2) There was significant difference between urea removal and fluid and sodium removal. Our results suggest that urea and creatinine removal do not represent other solutes and fluid removal. KT/Vurea and Ccr may thus not suit to be used alone to evaluate peritoneal dialysis adequacy.
