Immunophenotype and ultrastructure of B-cell lymphoproliferative disorder with cytoplasmic projection.
- Author:
Xinyue LIU
1
;
Xianshi HU
;
Lihua FAN
;
Youbing YUAN
Author Information
1. Institute of Hematology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Antibodies, Neoplasm;
blood;
Antigens, Differentiation, B-Lymphocyte;
blood;
Antigens, Neoplasm;
blood;
B-Lymphocytes;
immunology;
ultrastructure;
Bone Marrow Cells;
pathology;
Cytoplasm;
ultrastructure;
Female;
Humans;
Immunophenotyping;
Leukemia, Hairy Cell;
immunology;
pathology;
Lymphoma, B-Cell;
immunology;
ultrastructure;
Lymphoproliferative Disorders;
immunology;
pathology;
Male;
Middle Aged
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2003;23(3):236-238
- CountryChina
- Language:English
-
Abstract:
To identify the knowledge of rare lymphoproliferative disorder, the clinical and biological features of three kinds of lymphoproliferative disorders with cytoplasmic projections were compared. The clinical manifestations, ultrastructure and immunophenotype were analyzed. The results showed that hairy cell leukemia (HCL), splenic lymphoma with villous lymphocyte (SLVL) and hairy cell leukemia-variant (HCL-V) had some common characters including splenomegaly, peripheral blood and bone marrow infiltration by villous lymphocyte and B lymphocyte immunophenotype; but these three disorders had specific features respectively. It was concluded that overall analysis of clinical and laboratory features might be contributive to the differential diagnosis of these three disorders.
