Fertilization rates following 109 half intracytoplasmic sperm injection cycles for in vitro fertilization-embryo transfer.
- Author:
Xin-yu GUO
1
;
Jin-yu ZHNAG
;
De-wei LIN
;
Yan YU
;
Ming-xiao GE
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Asthenozoospermia; Embryo Transfer; Female; Humans; Infertility, Male; therapy; Male; Pregnancy; Pregnancy Outcome; Retrospective Studies; Sperm Injections, Intracytoplasmic; Spermatozoa; abnormalities
- From: Journal of Southern Medical University 2010;30(8):1920-1922
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the clinical outcomes of half intracytoplasmic sperm injection (partial ICSI) treatment in infertile patients with potential fertilization failure.
METHODSA total of 109 partial ICSI cycles of in vitro fertilization-embryo transfer (IVF-ET) were classified into 5 groups, namely group A (infertile patients for unidentified causes, 17 cycles), group B (oligo-asthenozoospermia patients, 28 cycles), group C (teratozoospermia patients, 8 cycles), group D (primary infertile patients without definite causes, 31 cycles), and group E (secondary infertile patients without definite causes, 25 cycles). The fertilization rate and normal fertilization rate after IVF and ICSI were compared between the groups.
RESULTSSignificant differences were found in the fertilization rate following conventional IVF and ICSI in group A (53.1-/+38.8% vs 72.2-/+34.1%) and group D (58.8-/+31.6% vs 82.7-/+21.4%) (P<0.05), but not in groups B, C and E (P>0.05). The normal fertilization rates following IVF and ICSI in groups A, B, D, E were statistically different (P<0.05), but similar in group C (P>0.05).
CONCLUSIONICSI treatment may increase the fertilization rate of IVF-ET in patients with unexplained infertility and primary infertility, but not in patients with oligo-asthenozoospermia, teratozoospermia or secondary infertility.
