Clinical application of the transjugular intrahepatic portosystemic stent-shunt in the emergency treatment of esophagogastric varices bleeding due to cirrhosis.
- Author:
Li-ying YOU
1
;
Ying-chun LI
;
Dong YAN
;
Ying XU
;
Jing YANG
;
Li-hong YANG
;
Fang CHENG
;
Jin-hui YANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Esophageal and Gastric Varices; etiology; surgery; Female; Gastrointestinal Hemorrhage; etiology; surgery; Humans; Hypertension, Portal; etiology; surgery; Liver Cirrhosis; complications; surgery; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; methods
- From: Chinese Journal of Hepatology 2011;19(7):490-493
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effects of transjugular intrahepatic portosystemic stent-shunt (TIPS) in emergency treatment of esophagogastric varices bleeding for the cirrhosis patients.
METHODS39 cases with esophageal and gastric varices bleeding due to liver cirrhosis received TIPS and were followed-up for 1 to 12 months, the short-term effects including 24 hours haemostasis rates post TIPS, pressure gradient between portal vein and systemic circulation, average pressure of portal vein were observed. The levels of albumin, cholinesterase, total bilirubin and prothrombin time post TIPS were also evaluated were observed and evaluated.
RESULTS37 cases received TIPS successfully among the 39 patients, with a total effective rate of 94.87% (37/39) and the rate of hemostasis in 24 hours was 100%. PSG dropped from (30.44+/-7.68) cm H2O to (18.78+/-4.71) cm H2O, mean portal pressure declined from (38.22+/-7.40) cm H2O to (27.00+/-5.38) cm H2O (P is less than 0.01). No significant differences existed at the level of albumin(A) and cholinesterase (CHE) before and after operation (P is more than 0.05). The relapse rate of frame stenosis was 5.71% (2/35). The incidence rate of hepatic encephalopathy was 13.51% (5/37). The relapse rate of rehaemorrhagia was 2.86% (1/35). The incidence rate of hepatic failure was 2.70% (1/37). The death rate was 5.71% (2/35).
CONCLUSIONThe effect of TIPS in treating portal hypertension caused by liver cirrhosis is prominent and safe, and is worthy of clinical application.
