Determination of serum TRAb (TSH receptor antibodies) concentration in adults and basedow patients before and after I-131 treatment by RIA method
- Author:
Khoa Trong Mai
- Publication Type:Journal Article
- Keywords:
basedow
- MeSH:
Graves Disease;
Antibodies;
serum;
adult;
therapeutics
- From:Journal of Medical Research
2002;17(1):51-54
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Serum TRAb concentration in healthy and Basedow patients before and after I-131 treatment was measured by RIA (Radioimmunoassay) method. The results were as follows: We standardized RIA method for measuring TRAb. Serum TRAb concentration in healthy adults (n=20) was at undetectable level. Serum TRAb concentration in the Basedow patients before I-131 treatment was 326.98+/-206.21mM/ml (n=20), which are hundreds times higher in comparison with normal people. After I-131 treatment: 5/12 Basedow patients have TRAb concentrations in the threshold of indefectibility and in 7/12 patients were 127.67+/-59.21 mU/ml, lower than before treatment.
