Studies on chemical constituents of Zhuang medicine Excoecaria venenata and their cytotoxic activity.
- Author:
De-sheng NING
;
Xiao-xu YAN
;
Si-si HUANG
;
Ling CHENG
;
Juan LI
;
Zheng-hong PAN
- Publication Type:Journal Article
- MeSH:
Cell Line, Tumor;
Cell Proliferation;
drug effects;
Cell Survival;
drug effects;
Drugs, Chinese Herbal;
chemistry;
toxicity;
Euphorbiaceae;
chemistry;
Humans;
Plants, Medicinal;
chemistry;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2015;40(4):686-690
- CountryChina
- Language:Chinese
-
Abstract:
Fourteen compounds were isolated from 95% ethanol extract by silica gel, MCI, and ODS column chromatography. These compounds were respectively identified as quercetin (1), kaempferol (2), (+)-catechin (3), fraxin (4), protocatechuic acid (5), gallic acid (6), methyl gallate (7), ethyl gallate (8), apocynol A (9), baccatin (10), cerevisterol (11), ellagic acid (12), 3, 3',4'-tri-0-methylellagic acid(13) and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate(14) by analyzing their spectral data and comparing with the previously reported literatures. Except for gallic acid (6), all other compounds were isolated from this plant for the first time. Compounds 1, 2 and 6 showed moderate anti-proliferation activities on tumor cells.
