The method of monitoring sleep state and respiratory rhythm in freely moving rats.
- Author:
Jing WANG
1
;
Guang-fa WANG
;
Yi-ling LING
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Circadian Rhythm; physiology; Electroencephalography; methods; Monitoring, Physiologic; methods; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Physiological Phenomena; Sleep; physiology
- From: Chinese Journal of Applied Physiology 2004;20(3):310-312
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo devise a new method for testing the animal model of sleep apnea syndrome (SAS).
METHODSWe simultaneously monitoring the respiratory wave through a micro-pressure transducer and the electrical signals of both electrocorticogram (ECoG) and electromyogram (EMG), for detecting the sleep-wake states and the respiratory rhythm in rats. The recording data are analyzed by the manual-computer work.
RESULTSThe ECoG and EMG signals are stable and easily to distinguish. We can accurately detect the sleep-wake state and the sleep apnea events in rats by these signals.
CONCLUSIONThe method is reliable to test the small animal model of SAS, and is easily to operate.
