Typing human papilloma virus (HPV) infection in the warts of oral mucosa from HIV-positive patients.
- Author:
San-cheng MA
1
;
Jing HU
;
Jin ZHAO
;
Paul SPEIGHT
Author Information
- Publication Type:Journal Article
- MeSH: HIV Infections; virology; HIV Seropositivity; Humans; Mouth Diseases; virology; Mouth Mucosa; pathology; virology; Papillomaviridae; isolation & purification; Papillomavirus Infections; diagnosis
- From: West China Journal of Stomatology 2004;22(5):423-425
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo detect and type human papilloma virus (HPV) in the warts of oral mucosa from HIV-positive patients, and better understand the biological characters of these oral warts.
METHODSPolymerase chain reaction (PCR) was used to detect and type HPV infection by consensus HPV primers Gp5+/Gp6+ and specific HPV primers (HPV6/11, 16, 18, 31, 33) in 34 cases of oral mucosa warts from HIV-positive patients.
RESULTSThe HPV infection rate was 88.2% by consensus HPV primers Gp5+/Gp6+; the HPV infection rate of HPV6/11, 16, 18, 31 was respectively 47.06%, 11.67%; 2.94%, and 5.88% by specific HPV primers.
CONCLUSIONMost lesions of oral warts from HIV-positive patients are associated with the infection of HPV. The low risk HPV6/11 infection is more common than the high risk HPV16, 18, 31.