Primary Pulmonary Myxoid Liposarcoma with Translocation t(12;16)(q13;p11) in a Young Female Patient: A Brief Case Report.
10.4132/KoreanJPathol.2012.46.4.392
- Author:
Choonhee SON
1
;
Phil Jo CHOI
;
Mee Sook ROH
Author Information
1. Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
- Publication Type:Case Report
- Keywords:
Lung;
Liposarcoma;
In situ hybridization, fluorescence
- MeSH:
Bronchi;
Cytogenetics;
DNA;
Female;
Fluorescence;
Humans;
In Situ Hybridization;
In Situ Hybridization, Fluorescence;
Liposarcoma;
Liposarcoma, Myxoid;
Lung;
Neoplasm Metastasis;
Rare Diseases;
Recurrence;
Sarcoma;
Writing
- From:Korean Journal of Pathology
2012;46(4):392-394
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary liposarcoma of the lung is an extremely rare disease. To date, only 14 cases have been reported in the literature. We experienced a case of myxoid liposarcoma of the lung treated by surgery. The tumor was well-defined, solid, lobulated mass measuring 3.5x2 cm, involving the bronchus of the left lower lobe. Microscopically, myxoid liposarcoma was identified. The fluorescence in situ hybridization confirmed the presence of a reciprocal translocation involving DNA damage-inducible transcript 3 (DDIT3) and fused in sarcoma (FUS) genes. The patient is still alive with no recurrence or metastasis at the time of writing this report (on 20 months postoperatively). To our knowledge, this is the first cytogenetic case report of pulmonary myxoid liposarcoma.
