Primary Endometrial Squamous Cell Carcinoma: A Case Report and Review of Relevant Literature on Korean Women.
10.4132/KoreanJPathol.2012.46.4.395
- Author:
Sung Jong LEE
1
;
Hyun Joo CHOI
Author Information
1. Department of Obstetrics and Gynecology, St. Vincent's Hospital, The Catholic University of Korea School of Medicine, Suwon, Korea.
- Publication Type:Case Report
- Keywords:
Endometrium;
Carcinoma, squamous cell;
Human papillomavirus;
In situ hybridization;
Genes, p16
- MeSH:
Carcinoma, Squamous Cell;
Cervix Uteri;
Endometrium;
Female;
Genes, p16;
Humans;
Hysterectomy;
In Situ Hybridization;
Leiomyoma;
Middle Aged;
Oligonucleotide Array Sequence Analysis;
Uterine Hemorrhage
- From:Korean Journal of Pathology
2012;46(4):395-398
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare tumor with unclear pathogenesis. A 54-year-old postmenopausal woman presented with a 6-month history of vaginal bleeding. The patient was provisionally diagnosed with uterine submucosal leiomyoma. This was followed by total hysterectomy with a bilateral salpingo-oophorectomy under the laparoscopic guidance. Histopathologically, the tumor was PESCC which was accompanied by a lack of the tumor in the uterine cervix. The tumor showed positive immunoreactivity for p16INK4a. But there was no evidence of human papillomavirus (HPV) on in situ hybridization and HPV DNA chip analysis. We also present a review of the relevant literature on Korean women.
