Prognostic factors and associated models for metastatic renal cell carcinoma treated with targeted therapy.
10.3881/j.issn.1000-503X.2014.04.018
- Author:
Zheng ZHENG
1
;
Han-zhong LI
1
;
Yong-qiang LI
1
Author Information
1. Department of Urology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- MeSH:
Carcinoma, Renal Cell;
drug therapy;
secondary;
Humans;
Kidney Neoplasms;
drug therapy;
secondary;
Models, Theoretical;
Prognosis
- From:
Acta Academiae Medicinae Sinicae
2014;36(4):450-453
- CountryChina
- Language:Chinese
-
Abstract:
Since 2006, tyrosine kinase inhibitors and anti-angiogenic drugs have revolutionized the treatment of metastatic renal cell carcinoma by improving progression-free survival and overall survival. The prognostic factors in metastatic renal cell carcinoma treated by targeted therapy include anatomical, histological, clinical, biological, and molecular parameters. The accuracy of these prognostic factors are not high when applied alone. A renal cancer prognostic system that combines all these prognostic factors can improve the risk assessment of renal cancer and prognosis prediction, and thus guide clinical decision-making.
