Kidney-targeted drug delivery systems.
10.1016/j.apsb.2013.12.005
- Author:
Peng ZHOU
1
;
Xun SUN
1
;
Zhirong ZHANG
1
Author Information
1. Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- Keywords:
Kidney-targeted;
Liposomes;
Macromolecular carrier;
Nanoparticles;
Prodrug
- From:
Acta Pharmaceutica Sinica B
2014;4(1):37-42
- CountryChina
- Language:English
-
Abstract:
Kidney-targeted drug delivery systems represent a promising technology to improve drug efficacy and safety in the treatment of renal diseases. In this review, we summarize the strategies that have been employed to develop kidney-targeted drug delivery systems. We also describe how macromolecular carriers and prodrugs play crucial roles in targeting drugs to particular target cells in the kidney. New technologies render it possible to create renal targeting conjugates and other delivery systems including nanoparticles and liposomes present promising strategies to achieve the goal of targeting drugs to the kidney.
