Expression of E-cadherin in human embryo.
- Author:
Yun LIU
1
;
Fu-qi XING
Author Information
- Publication Type:Journal Article
- MeSH: Blastocyst; metabolism; Cadherins; genetics; metabolism; Embryo Implantation; Embryo, Mammalian; metabolism; Female; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Developmental; Humans; Microscopy, Confocal; Pregnancy
- From: Chinese Journal of Medical Genetics 2003;20(4):348-349
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the role of calcium dependent adhesion molecules (cadherin) during the implantation and development of human embryo by studying the expression of E-cadherin in human embryo and blastocysts.
METHODSExpression of E-cadherin in preimplantation embryos and blastocysts was detected by indirect immunofluorescence assay and quantitated by laser scanning confocal microscopy.
RESULTSExpression of E-cadherin was found in all the preimplantation embryos and blastocysts the present authors studied. The expression was higher in blastocysts than that in preimplantation embryos.
CONCLUSIONThe above results suggested that human embryos and blastocysts could express E-cadherin and the expression increased during their development. These may be of significance to the adhesion and implantation of the human embryo and blastocysts.
