The popularization and application of cold storage red blood cells or whole blood at -80 degrees C of the Rh (D) negative patients in surgical operation.
- Author:
Zhongqing YU
1
;
Lihua HU
;
Min HAN
;
Shenzong RAO
;
Chengwei LUO
Author Information
1. Department of Blood Transfusion, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022.
- Publication Type:Journal Article
- MeSH:
Adult;
Blood Preservation;
methods;
Blood Transfusion;
methods;
Cryopreservation;
Erythrocytes;
Female;
Humans;
Intraoperative Care;
Male;
Middle Aged;
Rh-Hr Blood-Group System
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2002;22(2):155-157
- CountryChina
- Language:English
-
Abstract:
The efficiency of cold storage red blood cells (CSRBC) or whole blood at -80 degrees C used in 27 Rh (D) negative patients during surgical operation was reported. The Rh (D) negative patients received the transfusion of CSRBC or whole blood stored at -80 degrees C for 180 to 360 days. The changes in the indexes, such as blood TB, DB, K+, Na+, BUN, Cr, urine protein (URPO), UOB, Hb, HCT, serum total protein, relative to hemolytic reaction and blood volume before and after transfusion were observed. The results showed that after transfusion of CSRBC or whole blood 27 cases were negative for urine protein and UOB, and the levels of BUN and Cr were normal (P > 0.05). Blood TB, DB, Hb, and HCT were increased, while pH, blood K+ and blood Na+ was normal with the difference being not significant before and after operation (P > 0.05). Plasma protein was decreased, but there was no significant difference before and after operation (P > 0.05). It was suggested that CSRBC or whole blood at -80 degrees C could be safely infused to the Rh(D) negative patients without side effects during the surgical operation.
