Application feasibility of low tube voltage and lower iodine concentration contrast medium as well as iterative reconstruction in coronary computed tomography angiography
10.3760/cma.j.issn.0253-3758.2015.03.010
- VernacularTitle:低管电压、低碘浓度对比剂及迭代重建在冠状动脉CT血管成像中的应用
- Author:
Lei HAN
1
;
Weihua YIN
;
Bin LYU
;
Nan LI
;
Zhihui HOU
;
Shiliang JIANG
Author Information
1. 100037,中国医学科学院北京协和医学院国家心血管病中心心血管病国家重点实验室阜外心血管病医院放射科
- Keywords:
Tomography,X-ray computed;
Contrast media;
Radiation dosage
- From:
Chinese Journal of Cardiology
2015;43(3):234-238
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility of using lower iodine concentration 270 mgI/ml) contrast medium,lower X-ray tube voltage (100 kVp) and iterative reconstruction (IR) to reduce both iodine load and radiation dose but keep the image quality of coronary CT angiography (CCTA).Methods A total of 80 consecutive patients with suspected coronary artery disease were prospectively assigned to one of two groups via computer central system from January to May 2013.The control group (n =40) was scanned using dual-source CCTA protocols of 120 kV,370 mgI/ml Iopromide and filtered back projection reconstruction with a vascular algorithm (B26f).The study group (n =40) was scanned using 100 kV,270 mgI/ml Iodixanol and sinogram affirmed iterative reconstruction with a vascular algorithm (I26f).Other scan parameters and contrast injection protocol were similar between the two groups.Attenuation in the ascending aorta and coronary arteries along with image noise were measured.Images were reconstructed,measured and graded,and iodine load and effective radiation dose were calculated.Results The body mass index ((25.3 ± 3.0) kg/m2 vs.(25.4 ± 3.0) kg/m2,P =0.852),image quality scores (4.70 ±0.52 vs.4.63 ±0.59,P =0.545),mean signal-to-noise ratios (22.2 ±5.5 vs.23.6 ± 5.8,P =0.277),and contrast-to-noise ratios (35.6 ± 17.6 vs.41.1 ± 17.6,P =0.163) were similar between the control group and study group.Mean iodine loads were significantly reduced in the study group ((18.49 ± 0.75) g) compared to control group ((25.27 ± 0.94) g),P ＜ 0.001).Mean effective radiation doses were also significantly reduced in the study group ((2.31 ± 0.73) mSv) compared to that in control group ((3.52 ± 1.16) mSv),P ＜ 0.001).Conclusion Use of low X-ray tube voltage and iterative reconstruction allows lower iodine load and effective radiation dose application at CCTA without image quality reduction.
