Treatment of complicated cavernous venous malformation with retained copper wires combined with pingyangmycin injection.
- Author:
Si-Ming YUAN
1
;
Hui-Qing JIANG
;
Zhi-Jian HONG
;
Xiu-Kun WANG
;
Jun WANG
;
Xin-Bao HU
Author Information
- Publication Type:Journal Article
- MeSH: Arteriovenous Malformations; therapy; Bleomycin; analogs & derivatives; therapeutic use; Catheters, Indwelling; Child; Copper; therapeutic use; Female; Humans; Injections, Intralesional; Male; Young Adult
- From: Chinese Journal of Plastic Surgery 2009;25(5):343-346
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the therapeutic effect of retained copper wires combined with pingyangmycin (PYM) injection for complicated cavernous venous malformation.
METHODSThe location of venous malformation was detected by physical examination and MRI. The copper wires in 0.2 mm width were used to puncture the lesion repeatedly and retained in the lesion to form a net. After that, 8 mg PYM was injected into the residue malformed veins. 8-10 days later, the copper wires were taken out and necrotic tissue was squeezed out. The wounds of punctual holes healed through dressing. The patients received postoperative MRI to evaluate the therapeutic effect.
RESULTSFrom Jan. 2002 to Dec. 2008, 45 cases were treated. The patients were followed up for 1-3 years. 51.1% (23/45) of the lesions shrinked markedly or even disappeared. 42.2% (19/45) of the lesions reduced. 6.67% (3/45) of the lesions didn't change. There was no complication like invasive infection.
CONCLUSIONSIt is very effective to treat complicated cavernous venous malformation with retained copper wires combined with pingyangmycin injection.
