Effect of liposuction on adipokines, inflammatory markers and insulin resistance.
- Author:
Gui-e MA
1
;
Ping LIU
;
Hua LEI
;
Jian CHEN
;
Zhen-jun LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adipokines; blood; Adiponectin; blood; Adult; Female; Humans; Insulin Resistance; Interleukin-6; blood; Lipectomy; Lipid Metabolism; Middle Aged; Tumor Necrosis Factor-alpha; blood
- From: Chinese Journal of Plastic Surgery 2010;26(1):26-28
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of large-volume liposuction on adipokines, inflammatory markers and insulin resistance and its significance.
METHODSThe levels of serum adiponectin, resistin, IL-6, TNF-alpha, CRP and insulin sensitivity were measured pre- and 3 months postoperatively in 16 consecutive patients undergoing liposuction.
RESULTSThe adiponectin postoperative [(5.56 +/- 1.03) ng/ml] was significantly higher than the preoperative [(6.54 +/- 1.27) ng/ml] (P<0.05); the resistin postoperative [(6.30 +/- 3.25) pg/ml] is significantly lower than the preoperative [(5.18 +/- 2.28) pg/ml] (P<0.05); the insulin sensitivity postoperative (-3.78 +/- 0.39) significantly increased compared to the preoperative (-3.48 +/- 0.32, P<0.05); the TNF-alpha postoperative [(0.19 +/- 0.02) pg/ml] significantly increased compared to the preoperative [(0.23 +/- 0.03) pg/ml, P<0.01]; the postoperative IL-6 [(0.27 +/- 0.04) pg/ml] was similar to the preoperative [(0.31 +/- 0.06) pg/ml, P >0.05]; the postoperative CRP [(8.03 +/- 6.01) mg/L] was not significantly different with the preoperative [(7.28 +/- 6.21) mg/L, P>0.05].
CONCLUSIONSLarge-volume liposuction has good effect on insulin resistance and adipokines.
