Delaying vascular aging with Chinese medicine: implications from an overview of the p53 and miR-34s family.
10.1007/s11655-011-0823-y
- Author:
Ming WANG
1
;
Yan LEI
Author Information
1. Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
- Publication Type:Journal Article
- MeSH:
Blood Vessels;
pathology;
Cellular Senescence;
Feedback, Physiological;
Humans;
Medicine, Chinese Traditional;
MicroRNAs;
metabolism;
Tumor Suppressor Protein p53;
metabolism
- From:
Chinese journal of integrative medicine
2011;17(8):635-639
- CountryChina
- Language:English
-
Abstract:
p53 is an important target for studying vascular aging. However, as people gradually learned more about the miR-34s and the relationship between miR-34s and p53, new research idea emerged. This paper tries to elaborate the feature of p53, microRNA and miR-34s in-depth, analyze the regulatory action of miR-34s on p53, and offer some new prevention and treatment prospects about vascular aging in Chinese medicine.
