Myelodysplastic syndromes associated with acquired hemoglobin H disease.
- Author:
Jun-yuan QI
1
;
Feng-kui ZHANG
;
Ze-ping ZHOU
;
Yu-ping ZHAO
;
Ren-chi YANG
;
Lin-sheng QIAN
;
Yi-zhou ZHENG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; complications; alpha-Thalassemia; complications
- From: Chinese Journal of Hematology 2007;28(5):327-329
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo report 7 cases of acquired hemoglobin H in myelodysplastic syndromes.
CASE DATA AND DISCUSSIONClinical materials of the 7 cases were retrospectively presented. Clinical features of the similar cases in literatures were reviewed. The criteria for diagnosis of this entity by Steensma and its pathogenesis were discussed.
CONCLUSIONThis entity is a new subtype of MDS with unique clinical features and pathogenesis, and might be a proper model in the study of MDS transformation.