Development of alpha-glucosidase inhibitor from medicinal herbs.
- Author:
Fang JI
1
;
Guochun XIAO
;
Li DONG
;
Zijiao MA
;
Jingman NI
Author Information
1. School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
- Publication Type:Journal Article
- MeSH:
Cell Line;
Drug Evaluation, Preclinical;
Enzyme Inhibitors;
isolation & purification;
pharmacology;
Glycoside Hydrolase Inhibitors;
Humans;
Plant Extracts;
isolation & purification;
pharmacology;
Plants, Medicinal;
chemistry
- From:
China Journal of Chinese Materia Medica
2010;35(12):1633-1640
- CountryChina
- Language:Chinese
-
Abstract:
Alpha-glucosidase inhibitor can reduce the postprandial hyperglycemia and have good effect on preventing and treating the diabetes and diabetic complication. Along with the application of acarbose which is a kind of alpha-glucosidase inhibitor, many research groups pay attention to the crude alpha-glucosidase inhibitor screened from the medicinal herbs in order to find new, safe, and effective medicine. The development of alpha-glucosidase inhibitor screened from the medicinal herbs and its evaluation in vivo and vitro as well as the varieties of the medicinal herbs that contain alpha-glucosidase inhibitor in recent 30 years were summarized in this paper.
