Chemical constituents from stem barks of Vernonia cumingiana.
- Author:
Jing LIU
1
;
Guangzhi DING
;
Shishan YU
Author Information
1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Plant Bark;
chemistry;
Plant Extracts;
analysis;
isolation & purification;
Plant Stems;
chemistry;
Vernonia;
chemistry
- From:
China Journal of Chinese Materia Medica
2010;35(11):1421-1424
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents from the stem barks of Vernonia cumingiana were investigated. Various chromatographic techniques such as silica gel chromatography, Sephadex LH-20, ODS column chromatography and HPLC were used to isolate and purify the constituents. The structures were elucidated by spectral methods. Twelve compounds were isolated from the 95% ethanol extract and their structures were elucidated as methyl 3,5-dicaffeoylquinate (1), methyl 3,4-dicaffeoylquinate (2), ethyl 3,4-dicaffeoylquinate (3), methyl 3,4,5-tricaffeoylquinate (4), stigmasterol (5), alpha-spinasterol (6), beta-sitosterol (7), 24-methylene-lanosta-9 (11)-en-3beta-acetate (8), ethyl gallate (9), di-n-butyl-phthalate (10), stearic acid (11) and palmitic acid (12). Compounds 1-12 were isolated from this plant for the first time.
