Application of quantitative fingerprint to amino acids composition analysis of Xingnao Tongluo injection.
- Author:
Jun-Hua HU
;
Xia LIN
;
Yan ZHONG
;
Hui LI
;
Jian-Xiong WU
;
Jia-Chun LI
;
Zhen-Zhong WANG
;
Wei XIAO
- Publication Type:Journal Article
- MeSH: Amino Acids; chemistry; Chromatography, High Pressure Liquid; methods; Drugs, Chinese Herbal; chemistry; Quality Control
- From: China Journal of Chinese Materia Medica 2014;39(10):1811-1815
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo control the quality of the product, quantitative fingerprint was used to evaluate the composition of the amino acids in the Xingnao Tongluo injection.
METHODThe method of the quantitative fingerprint to the amino acids composition was established through AccQ Tag precolumn derivatization. The quality was evaluated by the quantitative test of the amino acids and the similarity in ten batches.
RESULTThe Xingnao Tongluo injection contained 12 amino acids and the contents of these amino acids were stable. All the ten batches of the samples had similarity of more than 0.90.
CONCLUSIONThe method was accurate, feasible and could be a simple and effective way to evaluate the quality of the traditional Chinese medicine.