Research progress on effects of traditional Chinese medicines on proliferation, apoptosis and differentiation of bone marrow mesenchymal stem cells.
- Author:
Jian-Kang FANG
;
Yi-Ping ZHOU
;
Ma-Lin LI
- Publication Type:Journal Article
- MeSH:
Animals;
Apoptosis;
drug effects;
Bone Marrow Cells;
cytology;
Cell Differentiation;
drug effects;
Cell Proliferation;
drug effects;
Humans;
Medicine, Chinese Traditional;
methods;
Mesenchymal Stromal Cells;
cytology;
drug effects
- From:
China Journal of Chinese Materia Medica
2014;39(15):2834-2837
- CountryChina
- Language:Chinese
-
Abstract:
Bone marrow mesenchymal stem cells (BMSCs) are a kind of pluripotent stem cells derived from bone marrows, which can not only support hematopoiesis, but also have capabilities of multidifferentiation, high-proliferation and self-renewing. They have become one of hotspots in stem cell studies. Studies on in vitro intervention with BMSCs with TCMs have made remarkable progress in recent years. According to the findings, some traditional Chinese medicines can promote proliferation of BMSCs, some can inhibit the apoptosis of BMSCs, while others can induce BMSCs to differentiate into multiple cell types, such as osteoblast. Furthermore, some studies also involved relevant action mechanisms. The authors summarized the advance in relevant studies by reference to relevant literatures of this field.
