Clinical effect of Yisui decoction plus western medicine in treating multiple system atrophy.
- Author:
Pei-Ran ZHANG
;
Gai-Hui GUO
;
Wei-Hong GU
;
Zi-Yi ZHANG
;
Kang WANG
;
Miao JIN
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Humans;
Hypotension, Orthostatic;
drug therapy;
Male;
Medicine, Chinese Traditional;
adverse effects;
methods;
Middle Aged;
Multiple System Atrophy;
drug therapy;
Retrospective Studies;
Treatment Outcome
- From:
China Journal of Chinese Materia Medica
2014;39(15):2968-2971
- CountryChina
- Language:Chinese
-
Abstract:
To observe the clinical effect of Yisui decoction plus western medicine in treating multiple system atrophy patients, totally 65 patients from China-Japan Friendship hospital during 2008-2012 with complete clinical data and received consecutive traditional Chinese medicine and western medicine treatment for more than 3 months were observed changes of traditional Chinese medicine symptom score, part 1 of unified multiple system atrophy rating scale, orthostatic hypotension before treatment and after 3 months treatment. After 3 months treatment, total effective rate of traditional Chinese medicine symptom was 70.8%. Compared with before treatment, score of part 1 of unified multiple system atrophy rating scale was obviously reduced after 3 month treatment (P < 0.001). Ex- cept swallow function without significant improvement, the remaining projects of unified multiple system atrophy rating scale were im- proved obviously (P < 0.05), of which the most obvious differences were orthostatic symptoms, falls and intestinal function (P < 0.001). Orthostatic hypotension after 1 month treatment and 3 month treatment was obviously better than before treatment (P < 0.001). There was no significant difference in orthostatic hypotension between 1 month treatment and 3 month treatment. The research results show that Yisui decoction plus western medicine has a certain effect on improving clinical symptoms of multiple system atrophy patients, especially has a significant effect on orthostatic hypotension, and can maintain a stable clinical effect in a certain period of time.
