Influences of Gender and Age on the Prevalence and Complications of Nonalcoholic Fatty Liver Disease.
10.3881/j.issn.1000-503X.2017.04.007
- VernacularTitle:性别及年龄对非酒精性脂肪肝患病情况及伴发疾病的影响
- Author:
Mei-Juan CAI
1
;
Xiang-Nan KONG
1
;
Xiao-Yun ZHAO
1
Author Information
1. Laboratory Medicine Center of Qilu Hospital of Shandong University(Qingdao),Qingdao,Shandong 266035,China.
- Publication Type:Journal Article
- From:
Acta Academiae Medicinae Sinicae
2017;39(4):499-505
- CountryChina
- Language:English
-
Abstract:
Objective To investigate the effects of gender and age on the prevalence and complications of nonalcoholic fatty liver disease(NAFLD). Methods A total of 8429 NAFLD patients were selected from the Health Check-up Center and Outpatient Departments of Qilu Hospital of Shandong University(Qingdao).The questionnaire-based survey,physical examinations,biochemical tests,and liver ultrasonography were performed for all cases.Patients were divided into young group(<45 years),middle aged group(45 years≤age<60 years),and old group(≥60 years)according to age,and the clinical features and laboratory findings were analyzed. Results The proportion of male patients gradually decreased with age,while the proportion of female patients increased(P<0.01);The incidences of metabolic diseases showed significant difference among young group,middle aged group,and old group(P<0.01).Except for hyperlipidemia,the proportion of male patients with NAFLD-accompanied metabolic symdrome was significantly higher than that of female patients in all three age groups(all P<0.01). Conclusions The prevalence of NAFLD-accompanied metabolic syndrome disease is associated with age and gender.This finding is useful for the prevention and treatment of NAFLD.
