Epidemiological situation and the E gene evolution of dengue virus in Guangzhou, 2011
10.3760/cma.j.issn.0254-6450.2012.12.017
- VernacularTitle:广州市2011年登革病毒流行状况及E基因进化特征分析
- Author:
Li-Yun JIANG
1
;
Yi-Min CAO
;
Yang XU
;
Qin-Long JING
;
Qing CAO
;
Biao DI
;
Zhi-Cong YANG
Author Information
1. 510440,广州市疾病预防控制中心病毒免疫科
- Keywords:
Dengue virus;
E gene;
Epidemiological characters
- From:Chinese Journal of Epidemiology
2012;33(12):1273-1275
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiological characteristics of Dengue and the E gene of the new isolated strains.Methods Epidemiological data and serum samples were collected.Serotypes were detected by real-time PCR and virus was isolated in C6/36.E gene of the new isolated strains were sequenced and analyzed by Mega 4.0.Results The cases of Dengue reached at the peak during September and November,with Serotype 1,2 and 4 were involved.Five strains of serotype 1 were isolated,with 4 of them fell into the clad of Asia genotype,and 1 belonged to America/Africa genotype.Conclusion The strains isolated in Guangzhou showed a high identity to the Southeast Asian strains.There seemed high risk of outbreak of Dengue in this area,However,the Dengue virus might have already been localized.
