Study on the rates of infection and spontaneous clearance on HCV among HIV-infected men who have sex with men in China.
- Author:
Ming-hui AN
1
;
Xiao-xu HAN
;
Jing LIU
;
Hao WU
;
Xi CHEN
;
Lin LU
;
Jun-jie XU
;
Min ZHANG
;
Hong SHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; China; epidemiology; Coinfection; epidemiology; virology; HIV Seropositivity; HIV-1; Hepacivirus; Hepatitis C; epidemiology; virology; Homosexuality, Male; Humans; Male; RNA, Viral; blood; Remission, Spontaneous; Viral Load; Young Adult
- From: Chinese Journal of Epidemiology 2013;34(1):15-18
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThe aim of this study was to understand the rates of infection and spontaneous clearance on hepatitis C virus (HCV) among HIV-infected men who have sex with men (MSM) in China.
METHODSHIV-infected MSM from Shenyang, Beijing, Changsha and Kunming were selected to take the HCV antibody and HVC-RNA tests, and then classified into 'under recovery (RNA-/Ab+) ' or being chronic (RNA+/Ab+). Information on demography, CD4(+) T cell, HIV viral load and liver biochemical indicators were also collected.
RESULTSIn 513 HIV-infected MSM, the positive rate of HCV antibody was 1.94% (10/513) and the positive rate of HVC-RNA was 0.77% (4/513). Five patients showed clearance of HVC-RNA, spontaneously. These 5 patients had low levels of both alanine transaminase (ALT) and aspartate aminotransferase (AST), and with high level of CD4(+) T cells, when compared to those who were not able to clear the HVC-RNA.
CONCLUSIONCurrently, the HCV infection rate was still at quite low level among the HIV-infected MSM in China. Dynamic of HIV/HCV co-infection should be monitored so as to develop suitable strategy on prevention and treatment among this population, in China.
