Advances in the mechanism of mesenchymal stem cells in promoting wound healing.
- Author:
Wenjing ZHU
1
;
Haobo SUN
1
;
Guozhong LYU
2
;
Email: LUGUOZHONG@HOTMAIL.COM.
Author Information
1. Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China.
2. Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China
- Publication Type:Journal Article
- MeSH:
Cell Differentiation;
Cell Transdifferentiation;
Mesenchymal Stem Cell Transplantation;
methods;
Mesenchymal Stromal Cells;
cytology;
metabolism;
physiology;
Skin;
cytology;
metabolism;
Wound Healing;
physiology
- From:
Chinese Journal of Burns
2015;31(6):476-478
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells possess the ability of self-renewal and multiple differentiation potential, thus exert immunomodulatory effect during tissue repair. Mesenchymal stem cells can stimulate angiogenesis and promote tissue repair through transdifferentiation and secreting a variety of growth factors and cytokines. This review outlines the advances in the mechanism of mesenchymal stem cells in promoting wound healing, including alleviation of inflammatory response, induction of angiogenesis, and promotion of migration of mesenchymal stem cells to the site of tissue injury.
