Advances in the research of mechanism of protein ubiquitination in wound healing.
10.3760/cma.j.issn.1009-2587.2016.02.013
- VernacularTitle:蛋白质泛素化修饰调控创面愈合机制研究进展
- Author:
Shan WU
1
;
Min YAO
Author Information
1. Department of Burns and Plastic Surgery, Shanghai Third People's Hospital, Institute of Trauma Medicine, School of Medicine, Shanghai Jiao Tong University, Shanghai 201900, China.
- Publication Type:Journal Article
- MeSH:
Signal Transduction;
physiology;
Ubiquitin;
metabolism;
Ubiquitin-Protein Ligases;
physiology;
Ubiquitination;
Wound Healing;
physiology
- From:
Chinese Journal of Burns
2016;32(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Ubiquitin, a critical small molecular protein, plays an important role in regulating multiple signaling pathways. Ubiquitination is a post-translational modification induced by ubiquitin through an ATP-dependent enzyme catalyzed reaction. A large number of proteins in the complicated signaling network participate in wound healing. This paper reviews the research progress in regulation of ubiquitin and ubiquitination for wound healing processes regarding the recent years.