Advancement in the diagnosis and management of toxic epidermal necrolysis.
10.3760/cma.j.issn.1009-2587.2016.06.008
- Author:
Wei SUN
1
;
Dinghong MIN
;
Guanghua GUO
Author Information
1. Department of Burns, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
- Publication Type:Journal Article
- MeSH:
Diagnosis, Differential;
Humans;
Stevens-Johnson Syndrome;
diagnosis;
therapy
- From:
Chinese Journal of Burns
2016;32(6):341-344
- CountryChina
- Language:Chinese
-
Abstract:
Toxic epidermal necrolysis (TEN) is a potentially life-threatening condition usually attributed to severe adverse drug reactions. The evolvement of TEN, including extensive epidermal sloughing, fluid and electrolyte imbalances, hypermetabolism, immune dysfunction, sepsis and organs failure, are very similar to that of extensive burn. There is no unified therapeutic regimen for TEN due to its unclear pathogenesis.This article reviews the recent progress in regard to TEN in etiology, pathogenesis, diagnosis, differential diagnosis, treatment, new standard diagnostic approach, primary care, and supportive treatment.
