A Study of Protein S Deficiency in Antiphospholipid Syndrome.
- Author:
Yoon Sung NAM
1
;
Nam Keun KIM
;
Myung Seo KANG
;
Do Yeon OH
;
Kwang Yul CHA
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
- Publication Type:Original Article
- Keywords:
Antiphospholipid syndrome;
Protein S deficiency
- MeSH:
Abortion, Spontaneous;
Antiphospholipid Syndrome*;
Female;
Humans;
Immunoenzyme Techniques;
Pregnancy;
Protein S Deficiency*;
Protein S*
- From:Korean Journal of Fertility and Sterility
2001;28(2):105-110
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To evaluate the abnormality of protein S in patients with recurrent spontaneous abortion due to antiphospholipid syndrome. MATERIALS AND METHOD: Antigen and activity of protein S were analyzed by enzyme immunoassay and clotting method, respectively. RESULTS: Of 18 patients with antiphospholipid syndrome, 4 patients were found to have no abnormality of protein S. There were 14 cases of protein S abnormality. Among them, there were 8 cases of type 1, 1 case of type 2, and 5 cases of type 3 protein S deficiency. CONCLUSION: So in the workup of patients with recurrent spontaneous abortion due to antiphospholipid syndrome, the evaluation for protein S is required.
