A dynamics model describing edema and its physiological analysis.
- Author:
Wei YAO
1
;
Guanghong DING
;
Xueyong SHEN
;
Jianhua DAI
;
Ke CHENG
;
Er'yu CHEN
;
Ruishang DANG
;
Hu WEI
Author Information
1. Department of Mechanics, Fudan University, Shanghai 200433, China.
- Publication Type:Journal Article
- MeSH:
Edema;
physiopathology;
Humans;
Models, Biological;
Nonlinear Dynamics
- From:
Journal of Biomedical Engineering
2005;22(1):15-19
- CountryChina
- Language:Chinese
-
Abstract:
Edema is a common pathological symptom, but its development mechanism is unknown. Based on the bearings of pressure upon interstitium structure and substantial exchange between plasma and interstitial fluid, a dymamics model describing the development of edema was set up. The model's theoretical results showed that the variations of interstitium pressure and structure due to imbalance of substantial exchange may lead to the development of edema, which is in accordance with recent clinical researches. Discussions on the dynamic mechanism of the development of edema proposed that the best way to prevent edema is instituting treatment before the interstitial structure being destroyed.
