A novel orthopaedic biodegradable polymer and its biocompatibility.
- Author:
Jianguo LIU
1
;
Xin QI
;
Jikui GUAN
;
Xinxiang XU
;
Xuesi CHEN
;
Xiabin JING
Author Information
1. Department of Orthopedic Surgery, The First Teaching Hospital of JiLin University, Changchun 130021, China.
- Publication Type:Journal Article
- MeSH:
Absorbable Implants;
Animals;
Bone Substitutes;
Catalysis;
Female;
Lactic Acid;
chemistry;
Male;
Materials Testing;
Polyesters;
chemistry;
Polymers;
chemistry;
Rats;
Rats, Wistar
- From:
Journal of Biomedical Engineering
2005;22(1):25-29
- CountryChina
- Language:Chinese
-
Abstract:
Copolymer of polycaprolactone (PCL) and polylactic acid (PLA) was synthesized and catalyzed using Y (CF3COO)3/AL (I-Bu)3. The biocompatibility was evaluated by means of biochemistry, immunocytochemistry, and by cytotoxity test. This novel orthopedic biodegradable polymer can serve as an ideal orthopedic biodegradable implants, and adjustment of molecular weight and ratio of polymers can control its degradation period.
