A Case of Dyspnea Caused by Local Botulinum Toxin Type A Injection.
- Author:
Hoon Sub SO
1
;
Min Young MOON
;
Jung Su LEE
;
Ho Cheol KIM
;
Byung Chul KANG
;
Younsuck KOH
Author Information
1. Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. yskoh@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Botulinum toxin;
Type A;
Dyspnea
- MeSH:
Acetylcholine;
Botulinum Toxins;
Botulinum Toxins, Type A;
Brain;
Deglutition Disorders;
Dysphonia;
Dyspnea;
Humans;
Korea;
Laryngoscopy;
Muscles;
Neurologic Examination;
Neuromuscular Junction;
Physical Examination;
Surgery, Plastic;
Synapses;
Vocal Cords
- From:Korean Journal of Medicine
2013;84(6):851-854
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Botulinum toxin type A is widely used for functional improvement of muscles and aesthetic plastic surgery. It paralyzes the injected muscle by inhibiting acetylcholine release from synapses of neuromuscular junctions. We herein report a case of progressive respiratory distress after botulinum toxin injection at both the gastrocnemius and soleus muscles. The patient also showed ptosis, dysphonia, dysphagia, and general weakness. Vocal cord dysfunction was observed by laryngoscopy. Other neurologic examination findings, including those of the physical examination, brain MRI, and Jolly's test, were normal. To our knowledge, this is the first report of botulinum toxin injection associated with dyspnea (MRC dyspnea scale, grade 3) in Korea.
