Epidemiological study of thalasaemia among children in Xishuangbanna, Dehong and Nujiang of Yunnan province.
- VernacularTitle:云南边境10个少数民族儿童地中海贫血的流行病学调查
- Author:
Li-qin YAO
1
;
Tuan-biao ZOU
;
Fa-bin YANG
;
Li-sha HU
;
Qian CHEN
;
Li-mei FAN
;
Zhong-ming ZHAO
;
Jin-tao LIU
;
Xing-tian WANG
Author Information
- Publication Type:Journal Article
- MeSH: Child; Child, Preschool; China; epidemiology; Hemoglobins, Abnormal; genetics; Humans; Infant; Infant, Newborn; Minority Groups; Prevalence; Thalassemia; ethnology; genetics; alpha-Thalassemia; epidemiology; genetics; beta-Thalassemia; epidemiology; genetics
- From: Chinese Journal of Medical Genetics 2011;28(5):579-582
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the carrier rate of thalasaemia among the children of 10 minority ethnic groups in 3 border states (Xishuangbanna, Dehong and Nujiang) of Yunnan Province.
METHODSA total of 6562 samples of children under 10 years old were analyzed by blood cell automatic analysis and hemoglobin electrophoresis.
RESULTSThe overall carrier frequency of thalasaemia was highest (46.2%) in Dehong, and lowest (30.6%) in Nujiang. The carrier frequency of beta-thalasaemia was the highest (40.6%) in Achang, and lowest (2.5%) in Dulong. The carrier frequency of alpha-thalasaemia was the highest (22.1%) in Dai from Xishuangbanna, followed by Dulong (19.1%).
CONCLUSIONThalasaemia carrier rates were high among the children of 10 minority ethnic groups in Yunnan. There were regional differences in their incidences. The results provide a valuable basis for thalasaemia prevention in Yunnan minorities in the three border states.
