Fatal Pancreatic Panniculitis Associated with Acute Pancreatitis: A Case Report.
10.3346/jkms.2007.22.5.914
- Author:
Woo Sun LEE
1
;
Mi Yeon KIM
;
Sang Woo KIM
;
Chang Nyol PAIK
;
Hyung Ok KIM
;
Young Min PARK
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. yymmpark@hotmail.com
- Publication Type:Case Report
- Keywords:
Pancreatitis;
Fat Necrosis;
Panniculitis
- MeSH:
Acute Disease;
Biopsy;
Erythema/pathology;
Fatal Outcome;
Humans;
Male;
Middle Aged;
Necrosis;
Pancreas/pathology;
Pancreatitis/*complications/*mortality;
Pancreatitis, Alcoholic/diagnosis/pathology;
Panniculitis/*complications/*mortality;
Skin/pathology;
Skin Diseases/diagnosis/pathology;
Tomography, X-Ray Computed/methods
- From:Journal of Korean Medical Science
2007;22(5):914-917
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pancreatic panniculitis is a rare disease in which necrosis of fat in the panniculus and other distant foci occurs in the setting of pancreatic diseases; these diseases include acute and chronic pancreatitis, pancreatic carcinoma, pseudocyst, and other pancreatic diseases. This malady is manifested as tender erythematous nodules on the legs, buttock, or trunk. Histopathologically, it shows the pathognomonic findings of focal subcutaneous fat necrosis and ghost-like anucleated cells with a thick shadowy wall. We herein report a case of fatal pancreatic panniculitis that was associated with acute pancreatitis in a 50-yr-old man. He presented with a 3-week history of multiple tender skin nodules, abdominal pain and distension. Laboratory and radiologic findings revealed acute pancreatitis, and skin biopsy showed pancreatic panniculitis. Despite intensive medical care, he died of multi-organ failure 3 weeks after presentation.
