Clinical study on effect of chuankezhi injection in treating children with bronchial asthma.
- Author:
Jian-qin ZHAO
1
;
Jie SHAO
;
Wen-wei ZHONG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adolescent; Anti-Asthmatic Agents; therapeutic use; Asthma; complications; drug therapy; physiopathology; Child; Child, Preschool; Drugs, Chinese Herbal; therapeutic use; Female; Forced Expiratory Volume; Humans; Male; Peak Expiratory Flow Rate; Phytotherapy; Rhinitis, Allergic, Perennial; complications; drug therapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2004;24(6):511-513
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy and safety of chuankezhi injection to children with bronchial asthma.
METHODSSixty-eight children suffered from asthma and/or asthma complicated with allergic rhinitis were randomly divided into the treated group and the control group, who received treatment of chuankezhi injection and Ginkgo injection respectively. Clinical observation on daily-symptom scores, and lung functions as peak expiratory flow (PEF), and forced expiratory volume in one second (FEV1) were conducted.
RESULTSAfter treatment the median of symptomatic scores in the treated group was 6.0 (M25-M75: 4.9-21.5) and that in the control group was 10.0 (M25-M75: 6.19-27.5), showing significant difference between groups; significant improvement was shown in the treated group, in which the PEF variance rate was reduced to 4.3 +/- 5.1%, while in the control group, it was 5.9 +/- 6.7%, the difference between the two groups was significant. Similar result also showed in comparison of FEV1 rate.
CONCLUSIONChuankezhi is helpful in improving clinical symptoms, reducing PEF variance rate and enhancing lung function in children with bronchial asthma, so as to be benefit to the long-term stable alleviation of asthma.
