Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture.
- Author:
Hai-ying WANG
1
;
Yi-ping CHEN
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Albuminuria; drug therapy; Astragalus membranaceus; Diabetic Nephropathies; drug therapy; Drug Therapy, Combination; Drugs, Chinese Herbal; chemistry; therapeutic use; Female; Furans; therapeutic use; Glucosides; therapeutic use; Humans; Losartan; therapeutic use; Male; Middle Aged; Phytotherapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2004;24(7):589-592
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of Compound Fructus Arctii Mixture (FAM, consisted of Fructus Arctii and ethanol extract of Radix Astragalus membranaceus) in treating diabetic nephropathy.
METHODSUsing FAM to treat 31 patients with diabetic nephropathy and controlled by 23 patients treated with Losartan, the therapeutic course was 3 months for both groups, changes of clinical symptoms, blood glucose, lipid metabolism and urinary albumin were observed and compared.
RESULTSThe total effective rate in the treated group was 80.6% while in the control group 65.2%. The symptoms, urinary protein and albumin as well as lipid metabolism in the treated group all significantly improved after treatment (P<0.05), but in the control group improvement only showed in urinary albumin level (P<0.05).
CONCLUSIONFAM has the effects of reducing urinary protein in 24 hrs, lowering urinary albumin, improving blood glucose after meal and lipid metabolism.
