Effects of Guilin Watermelon Frost on the mRNA expressions of basic fibroblast growth factor in patients with uterine cervical columnar ectopy.
- Author:
Jiang QIU-YAN
1
;
Song JIN-LING
;
Mo HAI-XIA
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Cervix Uteri; cytology; Citrullus; Drugs, Chinese Herbal; pharmacology; Epithelium; drug effects; Female; Fibroblast Growth Factor 2; genetics; metabolism; Humans; RNA, Messenger; genetics
- From: Chinese Journal of Integrated Traditional and Western Medicine 2012;32(1):17-19
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the molecular biological effects of Guilin Watermelon Frost (GWF) on the mRNA expressions of basic fibroblast growth factor (bFGF) in patients with uterine uterine cervical columnar ectopy.
METHODSOne hundred and sixty patients with uterine cervical columnar ectopy were assigned to two groups by the random digit table. Patients in the treatment group were treated with local spray of GWF, while those in the control group were local applied with bFGF-collagen sponge. The mRNA expressions of bFGF of the uterine tissue were detected in the two groups before and after treatment using RT-PCR.
RESULTSBefore treatment the mRNA expression of bFGF in the uterine cervical columnar ectopy was 0.55 +/- 0.10 in the treatment group and 0.58 +/- 0.13 in the control group, without insignificant difference (P > 0.05). After treatment it significantly increased in the two groups, being 0.82 +/- 0.17 and 0.78 +/- 0.15 respectively, showing statistical difference from before treatment (P < 0.01). But no statistical difference existed between the two groups after treatment (P > 0.05).
CONCLUSIONGWF showed enhancement on the mRNA expressions of bFGF in patients with uterine cervical columnar ectopy.
