Risk factors and surgical treatment of recurrent gastrointestinal stromal tumor in the rectum.
- Author:
Yu-xin ZHONG
1
;
Zhi-xiang ZHOU
;
Wei PEI
;
Li-ming WANG
;
Fan WU
;
Yong-fu SHAO
;
Ping ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Gastrointestinal Stromal Tumors; pathology; surgery; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; surgery; Rectal Neoplasms; pathology; surgery; Retrospective Studies; Risk Factors
- From: Chinese Journal of Gastrointestinal Surgery 2008;11(6):545-547
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the risk factors and surgical treatment of recurrent gastrointestinal stromal tumors in the rectum.
METHODSThe clinical data of 24 cases,admitted to our hospital, were analyzed retrospectively. The possible risk factors were tested by chi(2)-test. The resectable rate and recurrent rate of recurrent cases were compared with the first-treated cases.
RESULTSThe tumors with biggest diameter >or=3 cm and high invasive risk had higher recurrent rates (chi(2)=4.874, P=0.027, chi(2)=6.659, P=0.010). The resectable rate of recurrent gastrointestinal stromal tumors in rectum was 64.3% (9/14), which was significantly lower than that of first-treated ones (23/24) (chi(2)=6.618, P=0.010). There was no significant difference of recurrent rate between the recurrent group and the first-treated group (chi(2)=1.459, P>0.05).
CONCLUSIONSThe size and invasive risk of tumor are associated with the recurrent rate of gastrointestinal stromal tumors in rectum. The resectable rate of recurrent gastrointestinal stromal tumors in rectum is significantly lower than that of first-treated ones, but recurrent rates are similar in the 2 groups.