Efficacy of cellulose on functional constipation.
- Author:
Bao-hua LIU
1
;
Xin-qing YANG
;
Dong-lin REN
;
Yi-jiang DING
;
Ke ZHAO
;
Qun QIAN
;
Guan-gen YANG
;
Dong WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Cellulose; therapeutic use; Constipation; drug therapy; Female; Humans; Male; Middle Aged; Prospective Studies; Treatment Outcome; Young Adult
- From: Chinese Journal of Gastrointestinal Surgery 2009;12(2):182-184
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the clinical efficacy and safety of cellulose on functional constipation.
METHODSA prospective, self-controlled, multicenter clinical trial of cellulose was conducted for 2 weeks in 240 patients with functional constipation according to the Rome III( criteria. Symptoms and characters of feces before and after the treatment were observed and evaluated according to a score scheme.
RESULTSIn the 240 patients, the frequencies of defecation increased and the characters of feces was improved significantly after 2-week treatment. There were no adverse reactions observed throughout the clinical trial. The total efficacy was 82.1% at day 7 and 90.7% at day 14. The satisfactory rate of doctors was 83.8% and of patients was 83.8%.
CONCLUSIONCellulose is effective and safe in the treatment of chronic functional constipation.
