Efficacy of laparoscopic sleeve gastrectomy on morbidly obese patients with type 2 diabetes mellitus.
- Author:
Xin-Xiang LI
1
;
Raul J ROSENTHAL
;
Cheng-Zhu ZHENG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Diabetes Mellitus, Type 2; complications; surgery; Female; Gastrectomy; methods; Humans; Laparoscopy; Male; Middle Aged; Obesity, Morbid; complications; surgery; Prospective Studies; Treatment Outcome; Young Adult
- From: Chinese Journal of Gastrointestinal Surgery 2009;12(3):269-272
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy of laparoscopic sleeve gastrectomy(LSG) on improving glycemic control of morbidly obese patients with type 2 diabetes mellitus.
METHODSProspective study of 30 type 2 diabetes mellitus(T2DM) patients with BMI > or = 35 undergone LSG was carried out. Pre- and post-operative clinical parameters associated with diabetes mellitus 6 months after operation were evaluated. Data collected included demographics, weight loss(BMI, EWL%), diabetes control (FPG, HbA1C) and ghrelin.
RESULTSFasting plasma glucose and glycosylated hemoglobin concentration tests and clinical outcomes suggested LSG resulted in significant improvement or resolution of T2DM in all the 30 patients with CR 63%(19/30) and PR 37%(11/30).
CONCLUSIONSLSG can lead to significant changes in controlling glycemia on morbidly obese patients with T2DM in 6 months. Long-term efficacy needs further follow-up.
