Impact of width of hepatectomy margin on survival after simultaneous liver and colorectal resection for colorectal cancer liver metastasis.
- Author:
Jun XIANG
1
;
Yi-hua HUANG
;
Ji CUI
;
Mei-jing HUANG
;
Lei WANG
;
Zu-li YANG
;
Jun-sheng PENG
;
Jian-ping WANG
Author Information
- Publication Type:Journal Article
- MeSH: Colorectal Neoplasms; pathology; Female; Hepatectomy; mortality; Humans; Liver; pathology; surgery; Liver Neoplasms; pathology; secondary; surgery; Male; Middle Aged; Retrospective Studies; Survival Rate
- From: Chinese Journal of Gastrointestinal Surgery 2009;12(4):342-345
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo elucidate an adequate hepatectomy margin for simultaneous liver and colorectal resection in colorectal cancer liver metastasis.
METHODSClinical data of 39 patients, undergone simultaneous liver and colorectal resection for colorectal cancer liver metastasis from August 1994 to December 2004, were analyzed retrospectively. Two groups were divided according to the width of hepatectomy margin:less than 1 cm in group A, and equal or more than 1 cm in group B. The data were analyzed and compared between the 2 groups using Kaplan-Meier survival analysis and Log-rank test.
RESULTSThere were 14 patients in group A and 25 patients in group B. No significant differences in gender, age, primary tumor invasion, lymph node metastasis, the number, distribution and size of liver metastasis, duration and blood lose of surgery were found between two groups. The median survival time was 17 months in group A, and 37 months in group B, and the overall 5-year survival rate in group B was much better than that in group A (19.8% vs 0, P<0.01).
CONCLUSIONSimultaneous liver and colorectal resection in colorectal cancer liver metastasis should be performed with a hepatectomy margin equal or more than 1 cm.
