Management of refractory ventricular tachycardia in patients with non-myxomas primary cardiac tumors
10.3760/cma.j.issn.0253-3758.2012.06.010
- VernacularTitle:原发性心脏非黏液性肿瘤介导的难治性室性心动过速的治疗
- Author:
Cui-Hong HOU
1
;
Jing WANG
;
Su-Fang HAO
;
Jian-Min CHU
;
Jie-Lin PU
;
Shu ZHANG
Author Information
1. 北京协和医学院中国医学科学院阜外心血管病医院
- Keywords:
Heart,neoplasms;
Tachyarrhythmias,ventricular;
Treatment outcome
- From:
Chinese Journal of Cardiology
2012;40(6):502-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical characteristics and treatment experience of patients with non-myxomas primary cardiac tumors accompanied with refractory ventricular tachycardia (VT).Methods Clinical and imaging data as well as therapy efficacy and outcome were analyzed in 10 patients with non-myxomas primary cardiac tumors accompanied with refractory VT.Results There were 5 male and 5 female patients in this cohort [ mean age ( 37.6 ± 18.2 ) years ].Palpitation was presented in all 10patients,7 patients experienced syncope,and 2 patients suffered from amaurosis.The diagnosis was made by combined use of transthoracic echocardiogTams,MRI,and CT scan.The time from symptom to diagnosis was (33.2 ± 36.7 ) months.Symptom-related VT was documented by ECG or Holter monitoring.MRI suggested lipoma in 7 patients,lymphoma in 1 patient and fibroma in another patient.Seven tumors were located in the left ventricle,1 in right atria,1 at peri-aortic root and 1 near right ventrieular outflow tract.Nine out of 10 patients received anti-arrhythmic drug therapy.The ventricular tachyarrhythmia disappeared after surgical tumor resection in 4 patients.All other patients who were treated with antiarrhythmic drugs,radiofrequency ablation or subtotal excision showed only suboptimal efficacy during (39.4 ± 25.1 ) months follow-up.Conclusion Surgical tumor removal is the best treatment strategy for the treatment of refractory ventricular tachycardia in patients with primary cardiac benign tumors.
